Method for extracting arterial input function and

专利名称：Method for extracting arterial input function

and application thereof to dynamic contrastenhanced magnetic resonance imaging

发明人：Jiun-Jie Wang,Yu-Chun Lin,Tsung-Han

Chan,Chong-Yung Chi,Shu-Hang Ng,Yau-YauWai

申请号：US13781059申请日：20130228公开号：US09131862B2公开日：20150915

专利附图：

摘要：The present invention discloses a method for extracting AIF and an applicationthereof to DCE-MRI. The method comprises steps: contacting a target tissue with acontrast agent to obtain a plurality of images; using the plurality of images to work outthe tissue concentration curve of the contrast agent in each voxel; calculating the purityof the tissue concentration curve of each voxel according to the tissue concentrationcurves; and extracting the voxel having the highest purity as the optimized arteriallocation; and extracting the tissue concentration curve of the voxel having the highestpurity as the arterial input function. The extracted AIF is applied to a pharmacokineticmodel to obtain associated pharmacokinetic parameters. The present invention not onlyimproves the accuracy and reliability of the derived quantitative indexes but alsopromotes the efficiency of the quantitative analysis.

申请人：CHANG GUNG UNIVERSITY

地址：Tao-Yuan TW

国籍：TW

代理机构：Muncy, Geissler, Olds & Lowe, P.C.

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