Derivatives of the insulinotropic peptide exendin-

专利名称：Derivatives of the insulinotropic peptide

exendin-4 and methods of productionthereof

发明人：Yukun Sun,Dengxi Wu,Wen Chen,Zhiyong

Zhu

申请号：US10704409申请日：20031107

公开号：US20040142866A1公开日：20040722

摘要：The present invention is directed to the development of novel exendin-4derivatives exhibiting advantageous glucose-regulatory properties, and to methods ofproducing these derivatives, including recombinant methods in which these derivativesare produced by cleavage of a fusion protein containing multiple copies of the exendin-4derivative peptide. The methods of the present invention can be used to simplify theprocess of producing the disclosed exendin-4 derivatives, thereby lowering the cost oftheir production.

申请人：SHANGHAI HUYAI BIO-LAB CO., LTD.

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