专利名称:PROTEIN KNOBS
发明人:MOYLE, WILLIAM, R.,XING, YONGNA申请号:US0235914申请日:20021108公开号:WO03040695A3公开日:20041111
摘要:Compositions containing a knob attached to a specific site of a protein andmethods of producing and using these compositions are disclosed. The compositionscomprise a knob, a tail portion and a protein portion. The protein portion contains asubstituted cysteine residue at the desired location of labeling. The tail portion is locatedat the terminal end of the protein portion. The knob is linked to the end of the tailportion and contains a cysteine residue. The substituted cysteine residue on the proteinportion and the cysteine residue on the knob form a disulfide bond, thereby tagging theprotein portion at the desired site with the knob.
申请人:MOYLE, WILLIAM, R.,XING, YONGNA
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